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  • Naltrexone ReVia® | Depade® | Generic
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  • Semaglutide Ozempic® | Wegovy®
  • Tirzepatide Mounjaro® | Zepbound®
  • Liraglutide Victoza® | Saxenda® | Generic

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  • Medication

    Naltrexone

    Generic

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    • Taken by mouth
    • FDA-approved

    Acamprosate

    Campral® | Generic

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    • Taken by mouth
    • FDA-approved

    Semaglutide

    Ozempic® | Wegovy®

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    • Injection
    • Off-label prescribing

    Tirzepatide

    Mounjaro® | Zepbound®

    Learn more
    • Injection
    • Off-label prescribing

    Liraglutide

    Victoza® | Saxenda® | Generic

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    • Injection
    • Off-label prescribing
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    Workit Flex vs. Workit Core

    See how our programs compare and choose the one that meets your needs.

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      Senior Director of Research
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Power over alcohol cravings, backed by medication and clinical guidance.

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Medication
  • Naltrexone
  • Acamprosate
  • Semaglutide
  • Tirzepatide
  • Liraglutide
FAQs
  • Pricing
  • Medication
  • Support & Billing
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Flex Locations
  • Texas
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  • Arizona
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GLP-1 risks and concerns

Semaglutide, tirzepatide, and liraglutide are glucagon-like peptide-1 (GLP-1) receptor agonists. As part of Workit Flex, GLP-1 medications are prescribed off-label to support a change in drinking behaviors. The prescribing of medications that have not been FDA-approved for alcohol use disorder for such purpose is based on the provider’s determination of clinical appropriateness, judgment, and available evidence.

Common side effects of GLP-1 medications include nausea, vomiting, constipation, diarrhea, decreased appetite, and weight loss. These symptoms are most likely to occur when starting or increasing the dose and often improve over time as your body adjusts.

Rarely, GLP-1s may cause more serious side effects, including:

  • Pancreatitis (inflammation of the pancreas), which can cause severe stomach pain or require hospitalization.
  • Gallbladder issues, such as gallstones or inflammation, especially during rapid weight loss.
  • Kidney problems, particularly if vomiting or diarrhea leads to dehydration.
  • Gastroparesis (slowed stomach emptying), which can lead to ongoing nausea, bloating, or early fullness.
  • Possible thyroid concerns: Animal studies linked GLP-1s to thyroid tumors, including medullary thyroid carcinoma. While this hasn’t been shown in humans, people with a personal or family history of this cancer or MEN2 syndrome should not take GLP-1s.
  • Vision changes: This can be due to non-arteritic anterior ischemic optic neuropathy, a rare condition that can cause sudden vision loss, or due to worsening of diabetic retinopathy (where rapid improvement in chronically elevated blood sugar can worsen vision). While not common, any sudden changes in vision should be reported immediately.

If you experience serious symptoms—such as severe abdominal pain, vision changes, or signs of dehydration—please contact your provider right away.

  • Semaglutide: View the Ozempic black box warning.
  • Tirzepatide: View the Mounjaro black box warning.
  • Tirzepatide: View the Zepbound black box warning.
  • Liraglutide: View the liraglutide black box warning.

For more information about these medications, see the manufacturers’ full Prescribing Information and Medication Guides, or talk to your healthcare provider. You are encouraged to report negative side effects of drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

All clinical and medical services are provided by licensed physicians and clinicians who are practicing as employees or contractors of independently owned and operated professional medical practices that are owned by licensed physicians. These medical practices include Workit Health (MI), PLLC, Workit Health (CA), P.C., Workit Health (NJ), LLC, Workit Health (OH), LLC, and any other Workit Health professional entity that is established in the future.

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